. Also known as Restore the Right Kidney Detoction.[Progressive studies on effects of traditional Chinese medicines on differentiation of human bone mesenchymal stem cells]. states "youguiyin-containing rabbit serum can induce BMSC differentiate into chondrocyte". I haven't found the full study yet.
According to [Research of You Gui Yin and MSCs interventional therapy on early avascular necrosis of the femoral head]., You Gui Yin can also increase VEGF levels.
[Effects of different concentrations of gubishu containing serum on the proliferation of rabbit articular chondrocytes in vitro culture].
"Articular chondrocytes were obtained from the cartilage of 1-month rabbit and cultured in vitro. They were randomly divided into 8 groups,blank and Gubishu groups in different concentrations (5%, 10%,15%, 20%), MTT assay method was adopted to observe the influence of Gubishu containing serum with different concentrations to the proliferation of chondrocytes after incubated 1, 3, 5, 7 and 9 days.
The proliferation of chondrocytes was dependent on the concentration in Gubishu groups. At same time point,there was significant value between every groups, 20% concentration was greatest (P<0.05); There was significant differences between 5%, 10% and 20% concentration of the blank groups at same time point (P<0.05), and was not between 15% and 20% concentration at the 1, 3, 5 and 7 days (P>0.05), 20% concentration of the blank group was greatest. 20% concentrations of Gubishu containing serum was significantly greater than 20% concentrations of blank group at the 1, 3, 5 and 7 days (P<0.05).
20% concentrations of Gubishu containing serum can significantly increase the proliferation of chondrocytes, and bring the logarithmic growth period forward to the 3 day."
Bunch of studies here that I need.
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