Sunday, March 7, 2010


Methods and use related to humanin and humanin-like peptides

"HN[humanin] [is] an antagonist of Bax and Bid"

Humanin has highly homologous effects amongst different species.

"The present invention relates to humanin and humanin-like peptides or a fragment or derivative thereof, for use in the treatment and/or prevention of bone- or cartilage disorders."

"Humanin analog HNG (S14G) stimulates chondrogensis by regulating resting and proliferating chondrocyte zone (R+P)"

"Humanin analog HNG (S14G) positively regulates chondrocyte differentiation process by regulating type-X collagen in the mouse growth plate"

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